COMPARISON OF PERI-OPERATIVE OUTCOMES OF ROBOT-ASSISTED VERSUS LAPAROSCOPIC RADICAL NEPHRECTOMY

Abstract

OBJECTIVE To compare the perioperative outcomes of robot-assisted radical nephrectomy vs laparoscopic radical nephrectomy in patients with renal cell carcinoma.

METHODOLOGY This randomized controlled trial is being conducted at the Sindh Institute of Urology and Transplantation (SIUT) located in Karachi, with the aim of assessing peri-operative outcomes between robot-assisted and laparoscopic radical nephrectomy in individuals diagnosed with renal cell carcinoma. Participants, aged between 18 and 65 years, regardless of gender, will be systematically allocated into two distinct groups through randomization. The investigation will analyze peri-operative metrics including surgical duration, volume of intraoperative blood loss, necessity for transfusions, and duration of hospital stay. Data will be analyzed utilizing SPSS version 26.0, and statistical significance will be ascertained at a significance level of p ≤ 0.05.

RESULTS Among 70 patients, the mean age was 54.40 ± 15.08 years in the RARN group and 58.11 ± 13.94 years in the LRN group, with males comprising 57.1% and 51.4%, respectively. Operative time >4 hours occurred in 45.7% vs. 28.6% (p=0.138); blood transfusion in 20.0% vs. 22.5% (p=0.771); and hospital stay >4 days vs. 28.6% (p=0.584).

CONCLUSION Robot-assisted and laparoscopic radical nephrectomy exhibited analogous peri-operative outcomes in individuals diagnosed with renal cell carcinoma. There were no statistically significant discrepancies observed in operative duration, requirement for blood transfusion, or length of hospitalization between the two surgical methodologies. These findings substantiate the clinical parity of both techniques in the immediate surgical management of renal neoplasms.