COMPARISON OF HEMODYNAMIC EFFECTS OF LIGNOCAINE AND DEXMEDETOMIDINE DURING EXTUBATION

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Sayed Makarram Ahmed Bukhari
Atif Nazir
Amna Aslam
Muzammil Abrar
Azhar Munir

Abstract

Endotracheal extubation often triggers significant hemodynamic responses due to sympathetic stimulation, leading to potential complications. This study compares the efficacy of lignocaine and dexmedetomidine in attenuating these responses. Fifty patients undergoing elective surgeries were randomized to receive either lignocaineor dexmedetomidine priorto extubation. Hemodynamic parameters, including heart rate (HR) and mean arterial pressure (MAP), were monitored. Results indicated that dexmedetomidine provided superior hemodynamic stability compared to lignocaine, suggesting its advantage in managing extubation-induced stress.

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COMPARISON OF HEMODYNAMIC EFFECTS OF LIGNOCAINE AND DEXMEDETOMIDINE DURING EXTUBATION. (2025). The Research of Medical Science Review, 3(3), 474-479. http://thermsr.com/index.php/Journal/article/view/776